NEWS

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ivdtools 0.2.5 (2026-09-11)

Method comparison

• Added Linnet constant-CV Deming and precision-profile Deming.
• Added replicate summaries and lambda = "replicates" for Deming regression.
• Added analytic, jackknife, rank-based, and Bootstrap confidence intervals.
• Added segmented analysis with breakpoints.
• Added median and Hodges–Lehmann Bland–Altman intervals.
• Added selectable percent-difference denominators for Bland–Altman and outlier analysis.

Other analyses

• Added paired ROC AUC comparisons using EP24 or DeLong methods.
• Added EP28-style nonparametric and biweight reference intervals, with parametric, type-6, and Huber methods retained.
• Added split_by_cutpoints() and split_by_factors() for preparing analyses.
• Added pooled-variance weighting to linearity analysis.
• Added sample-size calculations for Bland–Altman studies and proportion confidence intervals and target-value tests.

Precision and robustness

• Added EP05 precision reports, including confidence intervals and multisite designs.
• Expanded normality-test results and improved reference-outlier handling.
• Improved validation, printing, plotting, documentation, and regression tests.

ivdtools 0.2.4

Method comparison

• Added reference-scale breakpoints for segmented regression and Bland–Altman analysis.
• Added residual-SD weighted least squares and the corrected Passing–Bablok Algorithm I.
• Added confidence intervals for mean and median differences.
• Separated the Bland–Altman plotting axis from its percent-difference base.

ivdtools 0.2.3

Method comparison

• Standardized mcr() orientation: reference is X, candidate is Y, and bias is candidate minus reference.
• Added parametric and nonparametric Bland–Altman limits of agreement.

Commutability

• Added material_type_map and the EP30 and IFCC Part 3 workflows.
• Added unequal-replicate handling, position diagnostics, calibration checks, and non-blocking study-design checks.
• Added component-level IFCC uncertainty output and expanded validation, summaries, plots, and documentation.

Precision and maintenance

• Added report.precision() for EP05 summary tables.
• Improved validation, plotting, printing, documentation, and tests across the package.

ivdtools 0.2.2

Measurement uncertainty

• Removed uncertainty_bias(). Use uncertainty_type_a(), uncertainty_type_b(), and uncertainty_combine() instead.

ivdtools 0.2.1

Commutability

• Replaced the former new-point method with a replicate-data workflow.
• Added EP14 and IFCC Part 2 calculations, prediction intervals, bias comparisons, and expanded uncertainty.

ivdtools 0.2.0

New workflows

• Added linearity, interference, C5/C95, dilution, spike-recovery, and hook- effect analyses.
• Added measurement-uncertainty workflows and reference_bias().

Enhancements

• Expanded ROC graphics and analytical-sensitivity workflows.
• Expanded validation, S3 methods, plotting, and tests.

ivdtools 0.1.3 (2026-08-23)

Analytical sensitivity

• Added explicit precision-profile model selection to the former lob_lod_loq() workflow.

ivdtools 0.1.2 (2026-08-20)

Initial release

• Initial release.